Flow cytometry of peripheral blood has become the standard tool for the diagnosis and monitoring of Sézary syndrome. However, there is a sense of frustration among dermatologists and oncologist regarding the challenges in interpreting vague flow cytometry (FC) reports, which often include an array of numbers and percentages that are difficult to interpret and fail to elucidate quantitatively or qualitatively the presence or absence of an abnormal T cell population. From the clinicians' perspective, a report of the flow cytometric evaluation for Sézary syndrome should include the following items: presence or absence of abnormal T‐cells, phenotype of abnormal cells, and quantity of abnormal cells to disease burden and for staging.

中文翻译：

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Sézary 综合征和蕈样真菌病流式细胞术评估：临床医生的观点

外周血流式细胞术已成为诊断和监测 Sézary 综合征的标准工具。然而，皮肤科医生和肿瘤科医生对解释模糊流式细胞术 (FC) 报告的挑战感到沮丧，这些报告通常包括一系列难以解释的数字和百分比，并且无法定量或定性地阐明存在或不存在异常的 T 细胞群。从临床医生的角度来看，Sézary 综合征的流式细胞术评估报告应包括以下项目：异常 T 细胞的存在与否、异常细胞的表型以及异常细胞数量对疾病负担和分期的影响。