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Radiomics Response Signature for Identification of Metastatic Colorectal Cancer Sensitive to Therapies Targeting EGFR Pathway.
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2020-02-04 , DOI: 10.1093/jnci/djaa017
Laurent Dercle 1, 2 , Lin Lu 1 , Lawrence H Schwartz 1 , Min Qian 3 , Sabine Tejpar 4 , Peter Eggleton 5 , Binsheng Zhao 1 , Hubert Piessevaux 6
Affiliation  

The authors sought to forecast survival and enhance treatment decisions for patients with liver metastatic colorectal cancer by using on-treatment radiomics signature to predict tumor sensitiveness to irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) alone (F) or in combination with cetuximab (FC).

中文翻译:

用于确定对EGFR靶向疗法敏感的转移性结直肠癌的放射学反应特征。

作者试图通过使用治疗中的放射性标记来预测对伊立替康,5-氟尿嘧啶和亚叶酸钙(FOLFIRI)单独(F)或与西妥昔单抗联合使用的肿瘤敏感性,从而预测肝转移性大肠癌患者的生存率并增强治疗决策。 FC)。
更新日期:2020-02-04
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