Abstract The hydrothermal reaction of Ln(NO3)3·6H2O with H2tyia (H2tyia = 5-(triazol-1-yl) isophthalic acid) afforded the lanthanide organic frameworks (Ln-MOFs), [Eu2(tyia)3(H2O)3]n (1) and {[Ln2(tyia)3·(H2O)3]· 3H2O}n (Ln = Tb 2, Dy 3, Sm 4, Gd 5, and Nd 6). Compounds were characterized by routine methods: PXRD, elemental analysis, solid-state luminescence properties analysis, TGA, FT-IR, and single-crystal X-ray crystallography. In this work, the luminescent properties of 2, 4, 5, and 6 and the responsiveness of various chemical components contained in urine were investigated. These MOFs detect 1-naphthol (1-N), urinary thiodiglycolic acid (TDGA), uric acid (UA), and hippuric acid (HA), which are the final metabolites of carbaryl, vinyl chloride monomers, purine, and toluene, respectively. These new Ln-MOFs offer the potential for biomarkers or metabolic sensors and show excellent selective and sensitive luminescence detection of 1-N, TDGA, UA, and HA. Graphical Abstract

中文翻译：

---

六种新型镧系金属有机骨架作为发光传感器，用于检测尿液中的 1-N、TDGA、UA 和 HA

摘要 Ln(NO3)3·6H2O 与 H2tyia (H2tyia = 5-(triazol-1-yl)isophthalic acid) 的水热反应得到镧系元素有机骨架 (Ln-MOFs)，[Eu2(tyia)3(H2O)3 ]n (1) 和 {[Ln2(tyia)3·(H2O)3]·3H2O}n（Ln = Tb 2、Dy 3、Sm 4、Gd 5 和 Nd 6）。通过常规方法对化合物进行表征：PXRD、元素分析、固态发光特性分析、TGA、FT-IR 和单晶 X 射线晶体学。在这项工作中，研究了 2、4、5 和 6 的发光特性以及尿液中含有的各种化学成分的响应性。这些 MOF 可检测 1-萘酚 (1-N)、尿硫代二乙醇酸 (TDGA)、尿酸 (UA) 和马尿酸 (HA)，它们分别是甲萘威、氯乙烯单体、嘌呤和甲苯的最终代谢物. 这些新的 Ln-MOF 为生物标志物或代谢传感器提供了潜力，并显示出对 1-N、TDGA、UA 和 HA 的出色选择性和灵敏的发光检测。图形概要