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Ribosome-guided piRNA production.
Nature Cell Biology ( IF 17.3 ) Pub Date : 2020-02-03 , DOI: 10.1038/s41556-020-0464-5
Yuanhui Mao 1 , Shu-Bing Qian 1
Affiliation  

The ribosome decodes messenger RNAs and constructs proteins based on the genetic blueprint. Ribosomes also associate with non-coding RNAs, such as PIWI-interacting RNA (piRNA) precursors, during the meiotic pachytene stage. Intriguingly, the ribosome mediates pachytene piRNA biogenesis by guiding endonucleolytic cleavage of piRNA precursors.

中文翻译:

核糖体引导的piRNA生产。

核糖体解码信使RNA,并根据遗传蓝图构建蛋白质。在减数分裂的粗线期,核糖体还与非编码RNA(例如PIWI相互作用RNA(piRNA)前体)相关。有趣的是,核糖体通过指导piRNA前体的内切核酸酶切割介导粗线piRNA生物发生。
更新日期:2020-02-03
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