Sjogren’s syndrome is a chronic autoimmune disorder characterised by lymphocytic infiltration of exocrine glands that causes dysfunction in salivary and lacrimal glands.1 Clinical features include dry eyes, dry mouth, fatigue, muscle pain and swelling, in association with the production of serum autoantibodies.1 The neurological manifestations of Sjogren’s syndrome reach up to 70% of these patients and include peripheral neuropathy, aseptic meningitis, vasculitis, seizures, myelitis, cognitive dysfunction, optic neuropathies, parkinsonism and others.1 The most common neurological manifestations are characterised by axonal neuropathy, sensory neuronopathy and small fibre neuropathy.1 On the other hand, ataxias are a heterogeneous group of diseases that comprise genetic and non-genetic aetiologies. The non-genetic or sporadic ataxias are frequently related to autoimmune disorders.2 However, cerebellar ataxia is rarely described in Sjogren’s syndrome. It is mandatory to classify ataxia as related to cerebellar damage (cerebellar ataxia) or to peripheral neuropathy (sensory ataxia). Usually, patients with Sjogren’s syndrome may present with sensory ataxia related to a sensory neuronopathy.2 This study aimed to characterise the pattern of ataxia in Sjogren’s syndrome and also to describe cerebellar ataxia and cerebellar atrophy in some of these patients. Fourteen patients with confirmed Sjogren’s syndrome and ataxia were enrolled on this study. All patients fulfilled criteria for primary Sjogren’s syndrome according to the American-European Consensus Group, 2002 and underwent clinical evaluation. Complementary tests included serum autoantibodies Ro (SSA) and …

中文翻译：

---

干燥综合征的共济失调的特征。

非遗传性或散发性共济失调通常与自身免疫性疾病有关。2但是，在干燥综合征中很少描述小脑性共济失调。必须将共济失调归类为与小脑损伤（小脑共济失调）或周围神经病变（感觉性共济失调）有关。通常，患有干燥综合征的患者可能会出现与感觉神经元病相关的感觉性共济失调。2本研究旨在描述干燥综合征的共济失调模式，并描述其中一些患者的小脑性共济失调和小脑萎缩。这项研究纳入了14例确诊为干燥综合征和共济失调的患者。所有患者均符合2002年美国-欧洲共识小组的原发性干燥综合征标准，并接受了临床评估。