BACKGROUND Many meningiomas are detected incidentally and remain asymptomatic until intervention. The goal of this study was to describe the management and outcome in this group of surgically treated asymptomatic meningiomas. METHODS From 2004 to 2017, 45 patients with asymptomatic meningioma were surgically treated at Sahlgrenska University Hospital, and their medical records and imaging data were analyzed. The asymptomatic cases were matched with symptomatic ones with respect to age at diagnosis, location, WHO (World Health Organization) grade, and Simpson grade. RESULTS Time from diagnosis to surgery differed between the asymptomatic and symptomatic patients (8.6 vs. 1.3 months; p < 0.001). Of symptomatic patients, 32.6% still used anti-epileptic drugs > 1 year after surgery, compared with 7.7% of the asymptomatic (p = 0.003). Thirty-day complication rate was significantly higher among the asymptomatic cases (35.6% vs. 24.4%; 0.001), as well as the proportion of older asymptomatic individuals (> 70 years) experiencing postoperative complication compared with symptomatic patients of the same age group. CONCLUSION As expected, asymptomatic cases had smaller tumors and waited longer for surgery. Surprisingly, complication rate was significantly higher among asymptomatic cases compared with their symptomatic control. Taken into account that many asymptomatic tumors are removed surgically due to patient's wish, one might suggest a more restrictive approach, especially in the elderly.

中文翻译：

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手术治疗的无症状脑膜瘤的适应症和预后：单中心病例对照研究。

背景技术许多脑膜瘤被偶然发现并保持无症状直至进行干预。这项研究的目的是描述这组经手术治疗的无症状脑膜瘤的管理和结果。方法2004年至2017年，在萨尔格伦斯卡大学医院对45例无症状脑膜瘤患者进行了手术治疗，并对其医疗记录和影像学数据进行了分析。无症状病例与有症状病例在诊断年龄，位置，世卫组织（世界卫生组织）等级和辛普森等级方面相匹配。结果无症状和有症状患者从诊断到手术的时间有所不同（8.6个月和1.3个月； p <0.001）。在有症状的患者中，有32.6％的患者在术后1年后仍使用抗癫痫药，而无症状的患者中这一比例为7.7％（p = 0.003）。与相同年龄组的有症状患者相比，无症状病例的30天并发症发生率显着更高（35.6％vs. 24.4％; 0.001），以及较大的无症状个体（> 70岁）发生术后并发症的比例。结论如预期的那样，无症状病例的肿瘤较小，等待手术的时间更长。出乎意料的是，无症状病例的并发症发生率明显高于其对症控制。考虑到由于患者的意愿，许多无症状的肿瘤可以通过手术切除，因此可能建议采用限制性更强的方法，尤其是在老年人中。70岁）与同年龄段有症状的患者相比发生了术后并发症。结论如预期的那样，无症状病例的肿瘤较小，等待手术的时间更长。出乎意料的是，无症状病例的并发症发生率明显高于其对症控制。考虑到由于患者的意愿，许多无症状的肿瘤可以通过手术切除，因此可能建议采用限制性更强的方法，尤其是在老年人中。70岁）与同年龄段有症状的患者相比发生了术后并发症。结论如预期的那样，无症状病例的肿瘤较小，等待手术的时间更长。出乎意料的是，无症状病例的并发症发生率明显高于其对症控制。考虑到由于患者的意愿，许多无症状的肿瘤可以通过手术切除，因此可能建议采用限制性更强的方法，尤其是在老年人中。