Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.

中文翻译：

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蒸姜乙醇提取物对体重和体内脂肪损失的影响：一项随机，双盲，安慰剂对照的临床试验。

蒸姜汁乙醇提取物（SGE）是一种含有6种松香酚含量高的产品，被认为比其他生姜产品更有效。我们进行了一项为期12周，随机，双盲，安慰剂对照的临床试验，以确定SGE对体重和体内脂肪减少的影响。招募了80名健康肥胖参与者并将其随机分为SGE和安慰剂组。结果指标包括功效指标（体重，体重指数，身体组成和血液指标）和安全性。补充期后，SGE组的平均体重，体重指数和体脂水平显着低于安慰剂组。对于任何安全参数，均未观察到临床上的重大变化。这些结果表明，SGE是一种有效的抗肥胖药，不会引起明显的副作用。因此，补充SGE与改变生活方式可以有效控制体重和脂肪量。