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Chemoselective nucleophilic additions to perfluorocyclopentene: An efficient building block to highly fluorinated molecules
Journal of Fluorine Chemistry ( IF 1.7 ) Pub Date : 2020-01-30 , DOI: 10.1016/j.jfluchem.2020.109454
Ernest L. Alvino , Emeline C. Lochmaier , Scott T. Iacono , Abby R. Jennings

A number of new fluorinated molecules were synthesized utilizing the chemoselective nucleophillic addition to perfluorocyclopentene (PFCP). These compounds were prepared under relatively mild conditions, requirering little or no further purification, and obtained in high yield. Furthermore, the compounds were designed to have reactive end groups for ease of incorporation into a polymer or material. As such, additional transformations were utilized to demonstrate this and are also presented. These molecules show the diverse pool of compounds and reactive monomers that can be prepared via this versatile starting material.



中文翻译:

全氟环戊烯的化学选择性亲核添加剂:高度氟化分子的有效组成部分

利用向全氟环戊烯(PFCP)的化学选择性亲核加成反应,合成了许多新的氟化分子。这些化合物是在相对温和的条件下制备的,几乎不需要或无需进一步纯化即可获得,并且收率很高。此外,化合物被设计成具有反应性端基,以便于掺入聚合物或材料中。因此,还使用了其他转换来证明这一点,并进行了介绍。这些分子显示出可以通过这种多用途起始原料制备的化合物和反应性单体的多样性库。

更新日期:2020-01-31
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