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Lifestyle and environmental contributions to ovulatory dysfunction in women of polycystic ovary syndrome.
BMC Endocrine Disorders ( IF 2.8 ) Pub Date : 2020-01-30 , DOI: 10.1186/s12902-020-0497-6
Bingqian Zhang 1, 2, 3, 4 , Wei Zhou 1, 2, 3, 4 , Yuhua Shi 1, 2, 3, 4 , Jun Zhang 5 , Linlin Cui 1, 2, 3, 4 , Zi-Jiang Chen 1, 2, 3, 4, 6, 7
Affiliation  

BACKGROUND Polycystic ovary syndrome (PCOS) is the most common reason of anovulatory infertility. Environmental factor is one of the main causes of PCOS, but its contribution to ovulatory dysfunction in PCOS remains unknown. METHODS A total of 2217 infertile women diagnosed as PCOS according to Rotterdam criteria were recruited, including 1979 women with oligo-anovulation (OA group) and 238 women with normal -anovulation (non OA group). Besides, 279 healthy control women of reproductive age were enrolled as controls. RESULTS Frequencies of snoring (PCOS-OA group, PCOS-non-OA group, control group: 29.30% vs 18.10% vs 11.50%, P < 0.01), smoking (37.70% vs 28.10% vs 12.20%, P < 0.01), plastic tableware usage (38.30% vs 28.10% vs 25.40%, P < 0.01) and indoor decoration (32.10% vs 24.80% vs 16.80%, P < 0.01) were highest in PCOS-OA group. After adjusted for multivariable, difference remained significant between PCOS-OA group and the other two groups. PCOS-OA women preferred a meat favorable diet compared to PCOS-non-OA group (54.60% vs 41.30%, P < 0.01). There was no difference between three groups in exercise, frequency of insomnia, and alcohol consumption. CONCLUSIONS Smoking, snoring, hyper-caloric diet, plastic tableware usage and indoor decoration were found to be associated with an increased risk for ovulatory dysfunction in women suffering from PCOS.

中文翻译:

生活方式和环境对多囊卵巢综合征女性排卵功能障碍的影响。

背景技术多囊卵巢综合征(PCOS)是无排卵性不孕的最常见原因。环境因素是PCOS的主要原因之一,但其对PCOS排卵功能障碍的贡献仍未知。方法总共招募了2217名根据鹿特丹标准诊断为PCOS的不育女性,包括1979年有无排卵功能的女性(OA组)和238有无排卵功能的女性(非OA组)。此外,纳入279名育龄健康对照妇女作为对照。结果打频率(PCOS-OA组,PCOS-非OA组,对照组:29.30%vs.18.10%vs 11.50%,P <0.01),吸烟(37.70%vs 28.10%vs 12.20%,P <0.01),在PCOS-OA组中,塑料餐具的使用率最高(38.30%对28.10%对25.40%,P <0.01)和室内装饰(32.10%对24.80%对16.80%,P <0.01)最高。校正多变量后,PCOS-OA组与其他两组之间的差异仍然显着。与PCOS非OA组相比,PCOS-OA妇女更喜欢肉类有益的饮食(54.60%比41.30%,P <0.01)。三组运动,失眠频率和饮酒量之间无差异。结论发现吸烟,打s,高热量饮食,使用塑料餐具和室内装饰与罹患PCOS的妇女排卵功能障碍的风险增加有关。和酒精消耗。结论发现吸烟,打s,高热量饮食,使用塑料餐具和室内装饰与罹患PCOS的妇女排卵功能障碍的风险增加有关。和酒精消耗。结论发现吸烟,打s,高热量饮食,使用塑料餐具和室内装饰与罹患PCOS的女性排卵功能障碍的风险增加有关。
更新日期:2020-04-22
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