Background Sudan red or 1-[(2-methoxyphenyl)azo]-2-naphthol is a low molecular weight azoic agent widely used in industry, particularly in the production of hair dyes. The use of this product in the food industry is prohibited due to its potential carcinogenic effect, but no respiratory involvement has been reported to date. Case presentation We present the case of a 46-year-old female patient who had been working in a cosmetics packaging company for 20 years. The patient developed occupational asthma to a red azo dye known as Sudan red. The diagnosis was confirmed by specific bronchial provocation test. Induced sputum samples were obtained previously and in the 24 h following the procedure, with a rise in the percentage of eosinophils from 10 to 65%. Conclusions This report describes the case of a patient who developed OA caused by exposure to an azoic dye called Sudan red. The clinical and analytical features suggest a type 2-related asthma; however, we are not yet able to confirm the specific pathophysiological mechanism. The extensive use of azo dyes in industry means that it is particularly important to describe their implications for health, which are probably underestimated at present.

中文翻译：

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苏丹红染料：一种引起 2 型职业性哮喘的新剂。

背景苏丹红或1-[(2-甲氧基苯基)偶氮]-2-萘酚是一种低分子量的偶氮试剂，广泛用于工业，特别是在染发剂的生产中。由于其潜在的致癌作用，禁止在食品工业中使用该产品，但迄今为止尚未报告呼吸道受累。案例介绍 我们介绍一位在化妆品包装公司工作了 20 年的 46 岁女性患者的案例。患者因使用一种称为苏丹红的红色偶氮染料而患上了职业性哮喘。经特异性支气管激发试验确诊。诱导痰样本在之前和手术后 24 小时内获得，嗜酸性粒细胞百分比从 10% 上升到 65%。结论 本报告描述了一名患者因接触称为苏丹红的偶氮染料而发展为 OA 的病例。临床和分析特征提示 2 型相关哮喘；然而，我们还不能确定具体的病理生理机制。偶氮染料在工业中的广泛使用意味着描述它们对健康的影响尤为重要，目前这些影响可能被低估了。