Environmental Toxicology and Pharmacology ( IF 4.2 ) Pub Date : 2020-01-31 , DOI: 10.1016/j.etap.2020.103349 Francesca Caloni 1 , Paola Fossati 2 , Arturo Anadón 3 , Alessia Bertero 1
Beauvericin (BEA) is a natural bioactive compound, with a dual nature. On the one hand, the peculiar characteristics of its molecule confer to BEA interesting properties, such as antibacterial, antiviral, antifungal, antiparasitic, insecticidal and anticarcinogenic activities. On the other hand, it is a natural contaminant of food and feed commodities, and an emerging mycotoxin, but lacks a toxicological risk assessment evaluation for long term exposure. This review aims to provide a global and comprehensive overview on BEA from its biological activities, to its in vivo and in vitro toxicological effects covering the multifaceted nature of this substance.
中文翻译:
Beauvericin:美丽与野兽。
白霉素(BEA)是一种天然生物活性化合物,具有双重性质。一方面,其分子的独特特性赋予BEA有趣的特性,例如抗菌,抗病毒,抗真菌,抗寄生虫,杀虫和抗癌活性。另一方面,它是食品和饲料商品的天然污染物,是新兴的霉菌毒素,但缺乏长期暴露的毒理学风险评估。这篇综述旨在从其生物活性到涵盖该物质多方面性质的体内和体外毒理学作用,提供有关BEA的全球和全面概述。