Stem cell therapy is considered as a promising regenerative medicine for repairing and treating damaged tissues and/or preventing various diseases. But there are still some obstacles such as low cell migration, poor stem cell engraftment and decreased cell survival that need to be overcome before transplantation. Therefore, a large body of studies has focused on improving the efficiency of stem cell therapy. For instance, preconditioning of stem cells has emerged as an effective strategy to reinforce therapeutic efficacy. Adipokines are signaling molecules, secreted by adipose tissue, which regulate a variety of biological processes in adipose tissue and other organs including the brain, liver, and muscle. In this review article, we shed light on the biological effects of some adipokines including apelin, oncostatin M, omentin-1 and vaspin on stem cell therapy and the most recent preclinical advances in our understanding of how these functions ameliorate stem cell therapy outcome.

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深入了解脂肪因子以优化干细胞对组织再生的治疗效果

干细胞疗法被认为是一种很有前途的再生医学，用于修复和治疗受损组织和/或预防各种疾病。但在移植前仍需克服一些障碍，如细胞迁移率低、干细胞植入不良和细胞存活率下降。因此，大量研究集中在提高干细胞治疗的效率上。例如，干细胞的预处理已成为增强治疗效果的有效策略。脂肪因子是由脂肪组织分泌的信号分子，可调节脂肪组织和其他器官（包括大脑、肝脏和肌肉）中的各种生物过程。在这篇综述文章中，我们阐明了一些脂肪因子的生物学效应，包括 apelin、制瘤素 M、