Leber congenital amaurosis (LCA) is an inherited retinal dystrophy that is characterized by severe visual impairment in early infancy. We generated a human induced pluripotent stem cell (hiPSC) line, DKHi090-A, from peripheral blood mononuclear cells (PBMCs) of a patient with LCA, by using a Sendai virus-based gene delivery system. We confirmed that DKHi090-A has a nicotinamide mononucleotide adenyltransferase 1 (NMNAT1) mutation and normal karyotype. DKHi090-A line is pluripotent and is capable of multilineage differentiation. This cell line is registered and is available at the National Stem Cell Bank, Korea National Institute of Health.

莱伯先天性黑蒙症（LCA）是一种遗传性视网膜营养不良，其特征是婴儿早期严重视力障碍。我们使用基于仙台病毒的基因传递系统，从LCA患者的外周血单核细胞（PBMC）生成了人诱导的多能干细胞（hiPSC）系DKHi090-A。我们证实DKHi090-A具有烟酰胺单核苷酸腺苷酸转移酶1（NMNAT1）突变和正常的核型。DKHi090-A品系多能，能够进行多系分化。该细胞系已注册，可在韩国国立卫生研究院国家干细胞库中获得。