Over the past two decades, many studies reported the benefits of higher 25-hydroxyvitamin D [25(OH)D] concentrations for nonskeletal effects. Researchers found significant benefits in reducing risk of acute respiratory tract infections, many types of cancer, type 2 diabetes mellitus, premature death, and adverse pregnancy and birth outcomes. In addition, 25(OH)D concentrations are low for various reasons in several categories of people, including the obese, those with dark skin living at higher latitudes, the elderly, and those who do not eat much eggs, fish, meat, or vitamin D fortified milk. Measuring 25(OH)D concentrations is one way to both increase the awareness of vitamin D's importance in maintaining good health and to encourage vitamin D supplementation or increased solar ultraviolet-B exposure to sustain well-being throughout life by reducing disease incidence. Although 20 ng/ml seems adequate to reduce risk of skeletal problems and acute respiratory tract infections, concentrations above 30 ng/ml have been associated with reduced risk of cancer, type 2 diabetes mellitus, and adverse pregnancy and birth outcomes. Thus, judicious testing of 25(OH)D concentrations could reduce disease incidence and make treatment expenditures more cost-effective.

中文翻译：

---

有针对性的25-羟基维生素D浓度测量和维生素D3补充可以对患者和公共健康产生重要影响。

在过去的二十年中，许多研究报告了较高的25-羟基维生素D [25（OH）D]浓度可带来非骨骼作用。研究人员发现，在降低急性呼吸道感染，多种类型的癌症，2型糖尿病，过早死亡以及不利的妊娠和分娩结果的风险方面，它们具有显着的益处。此外，由于各种原因，肥胖者，高纬度地区深色皮肤的人，老年人以及不多吃鸡蛋，鱼类，肉类或食物的人中25（OH）D的浓度较低。维生素D强化牛奶。测量25（OH）D浓度是增加对维生素D'认识的一种方法 在保持良好健康，鼓励补充维生素D或增加日光紫外线B暴露以减少疾病发生率，维持一生中的幸福方面，具有重要意义。尽管20 ng / ml似乎足以降低骨骼问题和急性呼吸道感染的风险，但浓度高于30 ng / ml却与降低患癌症，2型糖尿病以及不良妊娠和分娩结果的风险有关。因此，明智地检测25（OH）D浓度可以减少疾病的发生，并使治疗费用更具成本效益。以及不良的妊娠和分娩结果。因此，明智地检测25（OH）D浓度可以减少疾病的发生，并使治疗费用更具成本效益。以及不良的妊娠和分娩结果。因此，明智地检测25（OH）D浓度可以减少疾病的发生，并使治疗费用更具成本效益。