In recent years, therapeutic conjugates have attracted considerable attention as a new class of drug due to their unique pharmacological properties, especially from the pharmaceutical community. Their molecular structure tunability, improved targeting specificity, and therapeutic efficacy have been demonstrated in a wide range of research and clinical applications. In this topical review, we summarize selected recent advances in bioconjugation strategies for the development of therapeutic conjugates, their emerging application in clinical settings, as well as perspectives on the direction of future research.

中文翻译：

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治疗性共轭趋势：从临床到临床。

近年来，治疗性缀合物由于其独特的药理特性，特别是来自药学界，已经作为新型药物引起了相当大的关注。在广泛的研究和临床应用中已证明了它们的分子结构可调性，改进的靶向特异性和治疗功效。在本专题综述中，我们总结了生物缀合物策略在治疗缀合物发展中的最新进展，它们在临床中的新兴应用以及对未来研究方向的看法。