Lysophosphatidic acid (LPA) species are present in almost all organ systems and play diverse roles through its receptors. Asthma is an airway disease characterized by chronic allergic inflammation where various innate and adaptive immune cells participate in establishing Th2 immune response. Here, we will review the contribution of LPA and its receptors to the functions of immune cells that play a key role in establishing allergic airway inflammation and aggravation of allergic asthma.

中文翻译：

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紫杉醇/溶血磷脂酸在免疫调节和哮喘中的作用。

溶血磷脂酸（LPA）种类几乎存在于所有器官系统中，并通过其受体发挥多种作用。哮喘是一种以慢性过敏性炎症为特征的气道疾病，其中各种先天性和适应性免疫细胞参与建立Th2免疫反应。在这里，我们将回顾LPA及其受体对免疫细胞功能的贡献，这些免疫细胞在建立过敏性气道炎症和过敏性哮喘加重中起关键作用。