In a mouse model of prion disease, blocking a major branch of the unfolded protein response selectively in astrocytes was highly neuroprotective, reducing neurodegeneration, reducing astrocyte reactivity and increasing longevity.

中文翻译：

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撤回支持。

在病毒疾病的小鼠模型中，选择性地阻断星形胶质细胞中未折叠的蛋白质反应的主要分支具有高度的神经保护作用，减少了神经变性，降低了星形胶质细胞的反应性并延长了寿命。