Peyronie’s disease (PD) has a negative impact on overall quality of life for many patients and their partners. There is a significant portion of patients who elect noninvasive therapy and in this scenario we have little data with which to counsel patients. We aim to evaluate long-term patient-reported outcomes in a cohort of men with PD who elected conservative treatment. We identified all males with a diagnosis of PD evaluated at our institution by a single provider between May 2012 and January 2018. We excluded men who were <18 years old or had undergone surgical or intralesional injection (ILI) treatments. A PD-specific questionnaire was sent to those who met our inclusion criteria. 88/514 patients completed the survey and met the inclusion criteria. Penile curvature subjectively improved in 49%, remained stable in 34%, and worsened in 17%. Penile shortening was reported in 89% of patients. Penile shortening subjectively improved in 27%, remained stable in 59%, and worsened in 14%. Roughly 60% reported worsened intercourse satisfaction and erectile function. 60% reported that PD had negatively impacted their self-esteem and 69% felt that PD negatively impacted their sexual partner. Patients who utilized penile traction therapy (PTT) were significantly more likely to report improvements in penile curvature, shortening, and ability to engage in penetrative intercourse. Our survey provides important data on patient-reported outcomes in men with PD electing nonsurgical and non-ILI interventions. Although 49% of men noted at least a mild subjective improvement in their curvature over time, a majority had declining erectile function, decreased intercourse satisfaction, and psychosocial distress. These data can be used when counseling patients with a new diagnosis of PD who are considering treatment options.

佩罗尼氏病 (PD) 对许多患者及其伴侣的整体生活质量产生负面影响。有很大一部分患者选择了无创治疗，在这种情况下，我们几乎没有数据可以为患者提供咨询。我们旨在评估一组选择保守治疗的 PD 男性患者的长期患者报告结果。我们确定了 2012 年 5 月至 2018 年 1 月期间在我们机构由单一提供者评估的所有诊断为 PD 的男性。我们排除了年龄 <18 岁或接受过手术或病灶内注射 (ILI) 治疗的男性。向符合我们纳入标准的人发送了一份针对 PD 的问卷。88/514 名患者完成了调查并符合纳入标准。49% 的阴茎曲率主观改善，34% 保持稳定，17% 恶化。89% 的患者报告阴茎缩短。27% 的阴茎缩短主观改善，59% 保持稳定，14% 恶化。大约 60% 的人报告说性交满意度和勃起功能恶化。60% 的人报告说 PD 对他们的自尊产生了负面影响，69% 的人认为 PD 对他们的性伴侣产生了负面影响。使用阴茎牵引疗法 (PTT) 的患者更有可能报告阴茎曲率、缩短和进行穿透性交的能力得到改善。我们的调查提供了关于选择非手术和非 ILI 干预措施的 PD 男性患者报告结果的重要数据。尽管 49% 的男性注意到随着时间的推移，他们的曲率至少有轻微的主观改善，但大多数人的勃起功能下降，性交满意度下降，和社会心理困扰。这些数据可用于为正在考虑治疗选择的新诊断的 PD 患者提供咨询。