Pulsed actomyosin contractions drive morphogenetic processes, but how cyclic frequencies and amplitudes of contractions are tuned to achieve processive shrinking of cell surfaces remains unclear. In this issue of Developmental Cell, Cavanaugh et al. (2020) use optogenetics and biophysical modeling to demonstrate how cells respond to different oscillatory force profiles.

中文翻译：

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轻推或推开：体内改变肌动球蛋白的脉搏曲线。

脉冲性肌动球蛋白收缩驱动形态发生过程，但如何调节循环频率和收缩幅度以实现细胞表面的持续性收缩尚不清楚。在本期《发育细胞》中，Cavanaugh等人。（2020）使用光遗传学和生物物理模型来演示细胞如何响应不同的振荡力剖面。