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Premortem Tumor Stress in Radioimmunotherapy.
Trends in Cancer ( IF 14.3 ) Pub Date : 2020-01-27 , DOI: 10.1016/j.trecan.2020.01.001
Ignacio Melero 1 , Maite Alvarez 2 , Luna Minute 2 , Pedro Berraondo 3
Affiliation  

Recent investigations (Rodriguez-Ruiz et al.) have established the counterintuitive idea that delaying apoptosis upon tumor irradiation by caspase 3 inhibition in tumor cells raises the immunogenicity of dying malignant cells.



中文翻译:

放射免疫疗法中的死前肿瘤应激。

最近的研究(Rodriguez-Ruiz等人)已经建立了与直觉相反的想法,即通过抑制肿瘤细胞中的caspase 3抑制肿瘤照射而延迟凋亡会提高垂死的恶性细胞的免疫原性。

更新日期:2020-01-27
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