The ability to grow by anaerobic CO oxidation with production of H₂ from water is known for some thermophilic bacteria, most of which belong to Firmicutes, as well as for a few hyperthermophilic Euryarchaeota isolated from deep-sea hydrothermal habitats. A hyperthermophilic, neutrophilic, anaerobic filamentous archaeon strain 1505 = VKM B-3180 = KCTC 15798 was isolated from a terrestrial hot spring in Kamchatka (Russia) in the presence of 30% CO in the gas phase. Strain 1505 could grow lithotrophically using carbon monoxide as the energy source with the production of hydrogen according to the equation CO + H₂O → CO₂ + H₂; mixotrophically on CO plus glucose; and organotrophically on peptone, yeast extract, glucose, sucrose, or Avicel. The genome of strain 1505 was sequenced and assembled into a single chromosome. Based on 16S rRNA gene sequence analysis and in silico genome-genome hybridization, this organism was shown to be closely related to the Thermofilum adornatum species. In the genome of Thermofilum sp. strain 1505, a gene cluster (TCARB_0867-TCARB_0879) was found that included genes of anaerobic (Ni,Fe-containing) carbon monoxide dehydrogenase and genes of energy-converting hydrogenase ([Ni,Fe]-CODH–ECH gene cluster). Compared to the [Ni,Fe]-CODH–ECH gene clusters occurring in the sequenced genomes of other H₂-producing carboxydotrophs, the [Ni,Fe]-CODH–ECH gene cluster of Thermofilum sp. strain 1505 presented a novel type of gene organization. The results of the study provided the first evidence of anaerobic CO oxidation coupled with H₂ production performed by a crenarchaeon, as well as the first documented case of lithotrophic growth of a Thermofilaceae representative.

某些嗜热细菌，其中大多数属于Firmicutes，以及从深海热液生境中分离出来的一些超嗜热Euryarchaeota，都知道通过厌氧CO氧化并从水中产生H ₂来生长的能力。在气相中存在30％CO的情况下，从堪察加（俄罗斯）的地温泉中分离出了嗜热，嗜中性，厌氧的丝状古细菌菌株1505 = VKM B-3180 = KCTC 15798。根据一氧化碳CO + H ₂ O→CO ₂  + H _2，使用一氧化碳作为能源，菌株1505可以岩石状生长; 一氧化碳混合葡萄糖和葡萄糖；并且在蛋白ept，酵母提取物，葡萄糖，蔗糖或Avicel上有机营养。对菌株1505的基因组测序并组装成单个染色体。基于16S rRNA基因序列分析和计算机基因组-基因组杂交，该生物被证明与嗜热丝菌物种密切相关。在Thermofilum sp。的基因组中。发现该菌株为1505菌株，其基因簇（TCARB_0867-TCARB_0879）包含厌氧（含Ni，Fe的）一氧化碳脱氢酶基因和能量转换氢化酶的基因（[Ni，Fe] -CODH–ECH基因簇）。与其他H ₂的测序基因组中出现的[Ni，Fe] -CODH–ECH基因簇相比-生产carboxydotrophs时，[镍，铁]的-CODH-ECH基因簇Thermofilum藻。菌株1505提出了一种新型的基因组织。该研究的结果提供了第一个证据，证明厌氧的CO氧化和火锅鱼产生的H ₂产生，以及第一个有记载的嗜热丝菌科植物石化生长的案例。