当前位置: X-MOL 学术Am. J. Transplant. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Dialysis facility referral and start of evaluation for kidney transplantation among patients treated with dialysis in the Southeastern United States.
American Journal of Transplantation ( IF 8.8 ) Pub Date : 2020-01-25 , DOI: 10.1111/ajt.15791
Rachel E Patzer 1, 2, 3 , Laura McPherson 1 , Zhensheng Wang 1 , Laura C Plantinga 2, 4 , Sudeshna Paul 5 , Matthew Ellis 6 , Derek A DuBay 7 , Joshua Wolf 8 , Amber Reeves-Daniel 9 , Heather Jones 10 , Carlos Zayas 11 , Laura Mulloy 11 , Stephen O Pastan 3, 4
Affiliation  

Variability in transplant access exists, but barriers to referral and evaluation are underexplored due to lack of national surveillance data. We examined referral for kidney transplantation evaluation and start of the evaluation among 34 857 incident, adult (18‐79 years) end‐stage kidney disease patients from 690 dialysis facilities in the United States Renal Data System from January 1, 2012 through August 31, 2016, followed through February 2018 and linked data to referral and evaluation data from nine transplant centers in Georgia, North Carolina, and South Carolina. Multivariable‐adjusted competing risk analysis examined each outcome. The median within‐facility cumulative percentage of patients referred for kidney transplantation within 1 year of dialysis at the 690 dialysis facilities in Network 6 was 33.7% (interquartile range [IQR]: 25.3%‐43.1%). Only 48.3% of referred patients started the transplant evaluation within 6 months of referral. In multivariable analyses, factors associated with referral vs evaluation start among those referred at any time differed. For example, black, non‐Hispanic patients had a higher rate of referral (hazard ratio [HR]: 1.22; 95% confidence interval [CI]: 1.18‐1.27), but lower evaluation start among those referred (HR: 0.93; 95% CI: 0.88‐0.98), vs white non‐Hispanic patients. Barriers to transplant varied by step, and national surveillance data should be collected on early transplant steps to improve transplant access.

中文翻译:

在美国东南部接受透析治疗的患者中,透析机构转诊和肾移植评估开始。

移植途径存在差异,但由于缺乏国家监测数据,转诊和评估障碍尚未得到充分探索。我们检查了 2012 年 1 月 1 日至 8 月 31 日期间来自美国肾脏数据系统 690 个透析设施的 34 857 名成人(18-79 岁)终末期肾病患者的转诊肾移植评估和评估开始, 2016 年,随后一直持续到 2018 年 2 月,并将数据与佐治亚州、北卡罗来纳州和南卡罗来纳州的九个移植中心的转诊和评估数据相关联。多变量调整后的竞争风险分析检查了每个结果。在网络 6 的 690 个透析机构中,在透析后 1 年内转诊接受肾移植的患者的机构内累计百分比中位数为 33.7%(四分位距 [IQR]:25.3%‐43. 1%)。只有 48.3% 的转诊患者在转诊后 6 个月内开始移植评估。在多变量分析中,在任何时间转诊的那些人中,与转诊和评估开始相关的因素是不同的。例如,非西班牙裔黑人患者的转诊率较高(风险比 [HR]:1.22;95% 置信区间 [CI]:1.18-1.27),但转介患者的评估开始时间较低(HR:0.93;95 % CI:0.88-0.98)与非西班牙裔白人患者相比。移植障碍因步骤而异,应收集有关早期移植步骤的国家监测数据,以改善移植机会。非西班牙裔黑人患者的转诊率较高(风险比 [HR]:1.22;95% 置信区间 [CI]:1.18-1.27),但转介患者的评估开始时间较低(HR:0.93;95% CI: 0.88-0.98),与非西班牙裔白人患者相比。移植障碍因步骤而异,应收集有关早期移植步骤的国家监测数据,以改善移植机会。非西班牙裔黑人患者的转诊率较高(风险比 [HR]:1.22;95% 置信区间 [CI]:1.18-1.27),但转介患者的评估开始率较低(HR:0.93;95% CI: 0.88-0.98),与非西班牙裔白人患者相比。移植的障碍因步骤而异,应收集有关早期移植步骤的国家监测数据,以改善移植的可及性。
更新日期:2020-01-25
down
wechat
bug