Multifunctional catalysts derived from the integration of discrete catalytic partners in a confined space represent an important approach to emulate some of the design philosophies of enzymes. In an effort to design concepts for highly active catalysts for CO₂ transformations, we synthesize and contrast the performance of two porous pyridinium frameworks. The activity is found to be significantly amplified by the introduction of the amine group on the ortho position of the pyridinium moieties. The resulting catalyst is capable of highly active and selective cycloaddition of aziridines with CO₂ to 5-substituted-2-oxazolidinone, even under ambient conditions (1 bar, 22 °C). Its high activity originates from CO₂ activation by the pendant amine group in the vicinity of the active species, which facilitates the subsequent catalytic steps.

从密闭空间中离散催化伙伴的整合中衍生出的多功能催化剂代表了一种模拟酶设计理念的重要方法。为了设计用于CO ₂转化的高活性催化剂的概念，我们合成并对比了两种多孔吡啶鎓骨架的性能。发现通过在吡啶鎓部分的邻位上引入胺基显着增强了该活性。所得的催化剂即使在环境条件（1巴，22℃）下也能够将活性高的氮杂环丁烷与CO ₂选择性环加成到5-取代的2-恶唑烷酮上。其高活性源自CO ₂ 在活性物种附近被侧基胺基活化，这有助于随后的催化步骤。