The on water reaction of sodium telluride with electrophiles has been explored. Na₂Te, generated in situ through the rongalite (sodium hydroxymethanesulfinate)‐promoted reduction of elemental tellurium, reacts with a wide variety of electrophiles, including strained heterocycles, haloalkanes, Michael acceptors, and aryl diazonium salts, providing simple and rapid access to a broad range of novel functionalised symmetrical tellurides. The methodology well tolerated the presence of versatile functional groups such as alchohols, amines, esters, nitriles, and sulfones and allowed the incorporation of tellurium atoms into biologically relevant natural‐derived products. Furthermore, in the case of the nucleophilic ring opening of epoxides and aziridines, a judicious tuning of the reaction conditions enabled the synthesis of unreported β‐hydroxy‐ and β‐amino‐ditellurides, which were further employed as precursors of new functionalised unsymmetrical dialkyl tellurides. The thiol−peroxidase catalytic activity of hydroxy‐ditellurides has also been investigated in order to compare their antioxidant properties with those of homologous tellurides.

中文翻译：

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菱铁矿促进水合成功能化碲化物和二碲化物

的水与亲电碲钠的反应已探索。Na ₂ Te，原位生成通过rongalite（羟基甲烷亚磺酸钠）促进的元素碲还原，可与各种亲电试剂反应，包括应变杂环，卤代烷烃，Michael受体和芳基重氮盐，可轻松快速地获得各种新颖的功能化对称碲化物。该方法很好地耐受了多种功能基团的存在，例如醇，胺，酯，腈和砜，并允许将碲原子掺入生物学上相关的天然来源产品中。此外，在环氧化物和氮丙啶的亲核开环的情况下，明智地调整反应条件可以合成未报告的β-羟基和β-氨基二碲化物，它们进一步被用作新的官能化的不对称二烷基碲化物的前体。还对羟基二碲化物的硫醇过氧化物酶催化活性进行了研究，以比较它们与同源碲化物的抗氧化性能。