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A Straightforward Approach to the Synthesis of Disubstituted Cyclopentenones
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-03-04 , DOI: 10.1002/ejoc.201901850 Mariane V. Roldão 1 , Luis Gustavo Souza-Filho 1 , Wanda P. Almeida 1, 2 , Fernando Coelho 1
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-03-04 , DOI: 10.1002/ejoc.201901850 Mariane V. Roldão 1 , Luis Gustavo Souza-Filho 1 , Wanda P. Almeida 1, 2 , Fernando Coelho 1
Affiliation
We describe an approach to prepare di‐substituted cyclopentenones with potential anti‐inflammatory activity, using MBH adducts as building blocks. The synthesis is based on a rhodium mediated 1,4‐addition and an intramolecular Friedel‐Crafts type reaction.
中文翻译:
直接合成二取代环戊烯酮的方法
我们描述了一种使用MBH加合物作为构建基来制备具有潜在抗炎活性的双取代环戊烯酮的方法。合成基于铑介导的1,4加成和分子内Friedel-Crafts型反应。
更新日期:2020-03-04
中文翻译:
直接合成二取代环戊烯酮的方法
我们描述了一种使用MBH加合物作为构建基来制备具有潜在抗炎活性的双取代环戊烯酮的方法。合成基于铑介导的1,4加成和分子内Friedel-Crafts型反应。