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Green synthesis of silver nanoparticles from Curcuma longa L. and coating on the cotton fabrics for antimicrobial applications and wound healing activity.
Journal of Photochemistry and Photobiology B: Biology ( IF 5.4 ) Pub Date : 2020-01-25 , DOI: 10.1016/j.jphotobiol.2020.111806
M Maghimaa 1 , Sulaiman Ali Alharbi 2
Affiliation  

The cotton fabrics are a cosmopolitan in usage due to their extraordinary features. The clothes are a very good medium for the growth of pathogenic microorganisms. The nanoparticles have diverse benefits in the biomedical field like drug carrier and as antimicrobials. The current investigation was aimed to synthesize the metallic silver nanoparticles (AgNPs) from the aqueous extract of Curcuma longa leaf and evaluating their antimicrobial and wound healing potential of AgNPs coated cotton fabric. The synthesized AgNPs were characterized by HR-TEM and FT-IR examinations. The formulated AgNPs were coated with cotton fabrics to test their efficiency against the pathogenic microorganisms. The existence of AgNPs in the cotton fabrics was confirmed via the SEM along with EDX analysis. The antimicrobial potential of fabricated AgNPs and its coated cotton fabrics was inspected against the human pathogenic strains. The wound healing efficacy was examined in the L929 cells. The HR-TEM analysis proved the existence of spherical shaped AgNPs. In the antimicrobial activity, the CL-AgNPs loaded cotton fabric was exhibited an appreciable decrease in the growth of pathogenic microorganisms. The crude extract, as well as formulated AgNPs, also exhibited the noticeable antimicrobial potency against the S.aureus, P.aeruginosa, S.pyogenes, and C.albicans. The AgNPs loaded cotton fabrics was displayed the potent wound healing activity in the fibroblast (L929) cells. Consequently, it was concluded that the formulated AgNPs from C.longa coated cotton fabrics may be utilized for the variety of applications in hospital patients and even medical workers to prevent the microbial infection.

中文翻译:

由姜黄(Curcuma longa L.)绿色合成银纳米颗粒,并涂覆在棉织物上用于抗菌应用和伤口愈合活性。

棉织物由于其非凡的功能而成为一种国际化的用途。衣服是病原微生物生长的很好的培养基。纳米颗粒在生物医学领域具有多种优势,如药物载体和抗菌剂。目前的研究旨在从姜黄叶片的水提取物中合成金属银纳米粒子(AgNPs),并评估涂有AgNPs的棉织物的抗菌和伤口愈合潜力。合成的AgNPs通过HR-TEM和FT-IR检查表征。用棉织物包被配制的AgNP,以测试其对病原微生物的功效。通过SEM和EDX分析证实了棉织物中AgNP的存在。检查了制成的AgNP及其覆盖的棉织物的抗微生物潜力,以对抗人类病原菌。在L929细胞中检查伤口愈合功效。HR-TEM分析证明存在球形AgNPs。在抗菌活性方面,载有CL-AgNPs的棉织物在病原微生物的生长中表现出明显的下降。粗提物和配制的AgNPs还表现出对金黄色葡萄球菌,绿脓杆菌,化脓性链球菌和白色念珠菌的显着抗菌效力。载有AgNPs的棉织物在成纤维细胞(L929)中显示出有效的伤口愈合活性。因此,得出的结论是由C.配制的AgNP。
更新日期:2020-01-26
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