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Nanoemulsions as delivery systems for lipophilic nutraceuticals: strategies for improving their formulation, stability, functionality and bioavailability.
Food Science and Biotechnology ( IF 2.4 ) Pub Date : 2020-01-24 , DOI: 10.1007/s10068-019-00731-4
Seung Jun Choi 1, 2 , David Julian McClements 3, 4
Affiliation  

The food and beverage industry often need to encapsulate hydrophobic functional ingredients in their products, including colors, flavors, lipids, nutraceuticals preservatives, and vitamins. Encapsulation can improve the handling, water-dispersibility, chemically stability, and efficacy of these functional ingredients. In this review article, we focus on the design of nanoemulsion-based delivery systems to encapsulate, protect, and deliver non-polar bioactive agents, such as vitamin A, D and E, β-carotene, lycopene, lutein, curcumin, resveratrol, and coenzyme Q10. Initially, the challenges associated with incorporating these different bioactives into foods are highlighted. The relative merits and drawbacks of different nanoemulsion fabrication methods are then discussed. Finally, examples of the application of nanoemulsions for improving the stability and bioavailability of various kinds of hydrophobic vitamins and nutraceuticals are provided.

中文翻译:


纳米乳液作为亲脂性营养保健品的输送系统:改善其配方、稳定性、功能性和生物利用度的策略。



食品和饮料行业经常需要在其产品中封装疏水性功能成分,包括色素、香料、脂质、营养保健品防腐剂和维生素。封装可以改善这些功能成分的操作性、水分散性、化学稳定性和功效。在这篇综述文章中,我们重点关注基于纳米乳液的递送系统的设计,以封装、保护和递送非极性生物活性剂,例如维生素 A、D 和 E、β-胡萝卜素、番茄红素、叶黄素、姜黄素、白藜芦醇、和辅酶Q10。首先,强调了将这些不同的生物活性物质融入食品中所面临的挑战。然后讨论了不同纳米乳液制造方法的相对优点和缺点。最后,提供了纳米乳液在提高各种疏水性维生素和营养保健品的稳定性和生物利用度方面的应用实例。
更新日期:2020-01-24
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