Smart Breath Analyzers were developed as sensing terminals of a telemedicine architecture devoted to remote monitoring of patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and home-assisted by non-invasive mechanical ventilation via respiratory face mask. The devices based on different sensors (CO2/O2 and Volatile Organic Compounds (VOCs), relative humidity and temperature (R.H. & T) sensors) monitor the breath air exhaled into the expiratory line of the bi-tube patient breathing circuit during a noninvasive ventilo-therapy session; the sensor raw signals are transmitted pseudonymized to National Health Service units by TCP/IP communication through a cloud remote platform. The work is a proof-of-concept of a sensors-based IoT system with the perspective to check continuously the effectiveness of therapy and/or any state of exacerbation of the disease requiring healthcare. Lab tests in controlled experimental conditions by a gas-mixing bench towards CO2/O2 concentrations and exhaled breath collected in a sampling bag were carried out to test the realized prototypes. The Smart Breath Analyzers were also tested in real conditions both on a healthy volunteer subject and a COPD suffering patient.

中文翻译：

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低成本的呼吸分析仪模块，采用户籍无创机械通气，可远程监测COPD患者。

智能呼吸分析仪是远程医疗体系结构的传感终端，致力于远程监测慢性阻塞性肺疾病（COPD）并通过呼吸面罩通过无创机械通气进行家庭辅助的患者。该设备基于不同的传感器（CO2 / O2和挥发性有机化合物（VOC），相对湿度和温度（RH＆T）传感器），可在无创通气过程中监测呼入双管患者呼吸回路呼气管路的呼吸空气治疗会议；传感器原始信号通过云远程平台上的TCP / IP通信以假名形式发送给国家卫生服务部门。这项工作是基于传感器的物联网系统的概念验证，具有可连续检查治疗效果和/或需要医疗保健的疾病任何恶化状态的观点。在受控的实验条件下，通过针对CO2 / O2浓度的气体混合台进行了实验室测试，并在采样袋中收集了呼气，以测试实现的原型。智能呼吸分析仪还在真实条件下对健康的志愿者受试者和患有COPD的患者进行了测试。