Erythrina alkaloids were identified at the end of the 19th century and today, more than 100 members of the erythrinane family have been isolated. They are characterized by a unique tetracyclic, α-tertiary spiroamine scaffold. Herein we detail our efforts towards the development of a divergent enantioselective synthesis of (+)-dihydro-β-erythroidine (DHβE) – one of the most prominent members of this intriguing family of natural products. 1 Introduction 2 Synthetic Strategy 2.1 First Generation 2.2 Second Generation 2.3 Third Generation 2.3.1 Radical Endgame 2.3.2 Completion of the Total Synthesis 3 Conclusion

中文翻译：

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开发刺桐生物碱的不同途径

Erythrina 生物碱在 19 世纪末被鉴定出来，今天，已经分离出 100 多个 erythrinane 家族成员。它们的特点是独特的四环、α-叔螺胺支架。在本文中，我们详细介绍了我们为开发 (+)-二氢-β-红氨酸 (DHβE) 的不同对映选择性合成所做的努力，DHβE 是这个有趣的天然产物家族中最突出的成员之一。1 引言 2 合成策略 2.1 第一代 2.2 第二代 2.3 第三代 2.3.1 激进残局 2.3.2 完成全合成 3 结论