Chemicals have improved our quality of life, but the resulting environmental pollution has the potential to cause detrimental effects on humans and the environment. People and biota are chronically exposed to thousands of chemicals from various environmental sources through multiple pathways. Environmental chemists and toxicologists have moved beyond detecting and quantifying single chemicals to characterizing complex mixtures of chemicals in indoor and outdoor environments and biological matrices. We highlight analytical and bioanalytical approaches to isolating, characterizing, and tracking groups of chemicals of concern in complex matrices. Techniques that combine chemical analysis and bioassays have the potential to facilitate the identification of mixtures of chemicals that pose a combined risk.

中文翻译：

---

在不断变化的环境中追踪复杂的化学品混合物


化学品改善了我们的生活质量，但由此产生的环境污染有可能对人类和环境造成有害影响。人类和生物群通过多种途径长期接触来自各种环境来源的数千种化学物质。环境化学家和毒理学家已经超越了检测和量化单一化学物质，转而表征室内外环境和生物基质中的复杂化学混合物。我们重点介绍用于分离、表征和跟踪复杂基质中关注的化学物质组的分析和生物分析方法。化学分析和生物测定相结合的技术有可能促进识别具有综合风险的化学混合物。