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Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial.
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2020-01-23 , DOI: 10.1002/ejhf.1743 Valentina Carubelli,Yuhui Zhang,Marco Metra,Carlo Lombardi,G Michael Felker,Gerasimos Filippatos,Christopher M O'Connor,John R Teerlink,Phillip Simmons,Robert Segal,Gabriella Malfatto,Maria Teresa La Rovere,Dianfu Li,Xiumin Han,Zuyi Yuan,Yali Yao,Benjamin Li,Lit Fui Lau,Giuseppe Bianchi,Jian Zhang,
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2020-01-23 , DOI: 10.1002/ejhf.1743 Valentina Carubelli,Yuhui Zhang,Marco Metra,Carlo Lombardi,G Michael Felker,Gerasimos Filippatos,Christopher M O'Connor,John R Teerlink,Phillip Simmons,Robert Segal,Gabriella Malfatto,Maria Teresa La Rovere,Dianfu Li,Xiumin Han,Zuyi Yuan,Yali Yao,Benjamin Li,Lit Fui Lau,Giuseppe Bianchi,Jian Zhang,
Istaroxime is a first‐in‐class agent which acts through inhibition of the sarcolemmal Na+/K+ pump and activation of the SERCA2a pump. This study assessed the effects of a 24 h infusion of istaroxime in patients hospitalised for acute heart failure (AHF).
中文翻译:
接受急性心力衰竭住院的患者接受24小时异羟肟酸输注治疗:一项随机,安慰剂对照试验。
Istaroxime是一流的药物,通过抑制肌膜Na + / K +泵和激活SERCA2a泵起作用。这项研究评估了在急性心力衰竭(AHF)住院患者中24小时输注异羟肟酸的效果。
更新日期:2020-01-23
中文翻译:
接受急性心力衰竭住院的患者接受24小时异羟肟酸输注治疗:一项随机,安慰剂对照试验。
Istaroxime是一流的药物,通过抑制肌膜Na + / K +泵和激活SERCA2a泵起作用。这项研究评估了在急性心力衰竭(AHF)住院患者中24小时输注异羟肟酸的效果。