This work reports a simple, metal free and cost-effective protocol for the preparation of tri substituted 1,3,5 triazine using graphene oxide as a carbo-catalyst. Substituted triazine can be synthesized in good to excellent yields under mild reaction conditions. Furthermore, the use of graphene oxide as a catalyst results in a product free from metal traces. Recyclability study shows that it can be recycled up to six cycles without significant loss in catalytic activity. To show the scalability of the developed methodology, gram scale synthesis was also carried out.

中文翻译：

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氧化石墨烯作为使用双胍和醇类合成三取代1,3,5-三嗪的碳催化剂

这项工作报告了一种简单，无金属且具有成本效益的方案，该方案使用氧化石墨烯作为碳催化剂来制备三取代的1,3,5三嗪。取代的三嗪可以在温和的反应条件下以良好的产率合成。此外，使用氧化石墨烯作为催化剂可得到不含金属痕迹的产物。可回收性研究表明，它最多可以回收六个循环，而不会显着降低催化活性。为了显示所开发方法的可扩展性，还进行了克级合成。