Fabrication of Antibacterial Nanofibers Composites by Functionalizing the Surface of Cellulose Acetate Nanofibers,ChemistrySelect

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Fabrication of Antibacterial Nanofibers Composites by Functionalizing the Surface of Cellulose Acetate Nanofibers
ChemistrySelect ( IF 1.9 ) Pub Date : 2020-01-24 , DOI: 10.1002/slct.201901106
Muhammad Qamar Khan _{1,

2} , Davood Kharaghani ₂ , Sanaullah ₂ , Amir Shahzad ₂ , Nam Phan Duy ₂ , Yohei Hasegawa ₂ , Azeemullah ₂ , Jungsoon Lee ₃ , Ick Soo Kim ₂

Affiliation

The surface modification of nanofibers web enables the invention of wound dressings by using the simple materials substrate without altering the mechanical properties of foundation materials or nanofibers web. Herein, authors fabricated the novel antibacterial wound dressings by functionalizing the surface of cellulose acetate (CA) nanofibers. This surface treatment was done through facile method. The silver sulfadiazine (SSD) nanoparticles were successfully synthesized on the surface of cellulose acetate nanofibers web by in‐situ facile method in which nanofibers webs were immersed in the solution of sodium sulfadiazine salt and silver nitrate (AgNO₃) for three different interval of times (hrs). The resultant CA/SSD nanofibers were characterized by scan electron microscope, transmission electron microscope, FT‐IR, XPS, XRD, water contact angle and antibacterial agar disc diffusion test. All characterization results supported that this composite can be used for antibacterial wound dressings, especially for gram negative E. Coli bacteria because SSD has great potential against E. Coli bacteria.

中文翻译：

通过功能化醋酸纤维素纳米纤维的表面制备抗菌纳米纤维复合材料。

纳米纤维网的表面改性使得能够通过使用简单的材料基材而不改变基础材料或纳米纤维网的机械性能来发明伤口敷料。本文中，作者通过功能化醋酸纤维素（CA）纳米纤维的表面来制造新型抗菌伤口敷料。该表面处理通过简便的方法进行。通过将纳米纤维网浸入磺胺嘧啶钠盐和硝酸银（AgNO _3）溶液中的原位简便方法，成功地在醋酸纤维素纳米纤维网表面上成功合成了磺胺嘧啶银（SSD）纳米颗粒。）的三个不同时间间隔（小时）。通过扫描电子显微镜，透射电子显微镜，FT-IR，XPS，XRD，水接触角和抗菌琼脂圆盘扩散测试对所得的CA / SSD纳米纤维进行表征。所有表征结果均支持该复合材料可用于抗菌伤口敷料，尤其是革兰氏阴性大肠杆菌，因为SSD具有抗大肠杆菌的巨大潜力。

更新日期：2020-01-24

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