Abstract In this study, the use of zinc ferrites in a magnetic, ultrasound-assisted dispersive micro solid-phase extraction procedure for the determination of sulfonamides is developed. Zinc ferrites can efficiently and selectively extract sulfonamides from environmental and food matrixes. Their synthesis is straightforward, and the resulting material exhibits favorable magnetic properties for its harvesting, after extraction. As a proof of concept, an analytical method was developed for the determination of sulfonamides in lake water and egg samples using high-performance liquid chromatography with diode array detection. The new procedure exhibits low limits of quantification (0.06 up to 0.11 μg L−1), low matrix effect (from −8% to 8%), acceptable recoveries (88–101%) and satisfactory enrichment factors (111–141). Moreover, the method has a wide linear range (up to 250 μg L−1) making it possible to determine sulfonamides at concentrations above and below the maximum residue limit. Due to the aforementioned merits, the few synthetic steps required and the efficiency of sample preparation, the developed method can be used for the routine analysis of sulfonamides. Moreover, this study highlights the affinity of zinc for sulfonamides, a property that has never reaped before in analytical chemistry.

中文翻译：

---

铁酸锌磁性吸附剂用于磺胺类分散微固相萃取及其高效液相色谱法测定

摘要 在本研究中，开发了在磁性超声辅助分散微固相萃取程序中使用铁酸锌测定磺胺类药物的方法。铁酸锌可以高效、选择性地从环境和食品基质中提取磺胺。它们的合成很简单，并且所得材料在提取后表现出有利的磁性能。作为概念验证，开发了一种使用二极管阵列检测的高效液相色谱法测定湖水和鸡蛋样品中磺胺类药物的分析方法。新程序表现出低定量限（0.06 至 0.11 μg L-1）、低基质效应（从 -8% 到 8%）、可接受的回收率（88-101%）和令人满意的富集因子（111-141）。而且，该方法具有较宽的线性范围（高达 250 μg L-1），因此可以测定浓度高于和低于最大残留限量的磺胺类药物。由于上述优点、所需的合成步骤少且样品制备效率高，所开发的方法可用于磺胺类药物的常规分析。此外，这项研究强调了锌对磺胺类药物的亲和力，这是分析化学中从未有过的特性。