Abstract Wastewater treatment plants are a major source of human pharmaceutical residues (PR) in the aquatic environment, which are considered to be of emerging concern. The microalga Chlamydomonas acidophila has shown to be a promising technology to recover the nutrients from wastewater and therefore, the aim of this study was to evaluate the ability of this species to also remove PRs commonly present in wastewaters (atenolol, caffeine, carbamazepine, clarithromycin, erythromycin, lidocaine, propranolol and simvastatin). Batch assays were carried out (50 mL, 90 rpm, 43 μmol photons m−2 s−1, 22 °C) comprising the wastewater with the pharmaceutical mixture at three concentrations: CHigh, CModerate and CEnv. The results demonstrated that this microalga does not seem to be affected by pharmaceuticals in wastewater at concentrations well above those detected in urban effluents; additionally it is able to degrade the antibiotics erythromycin and clarithromycin better than other microalgae species and enhances their removal from wastewater by 93–65 % and 64–50 %, respectively. Furthermore, it exhibited a high assimilation of ammonium and phosphates reaching values of around 9 mgNH4 L−1d−1 and 3 mgPO4 L−1d−1 compared to other species. Therefore, Chlamydomonas acidophila appears to be a promising agent for urban wastewater treatment.

中文翻译：

---

嗜酸衣藻从废水中去除药物和回收营养

摘要 污水处理厂是水生环境中人体药物残留 (PR) 的主要来源，这被认为是新出现的问题。微藻嗜酸衣藻已被证明是一种从废水中回收养分的有前途的技术，因此，本研究的目的是评估该物种去除废水中常见 PRs 的能力（阿替洛尔、咖啡因、卡马西平、克拉霉素、红霉素、利多卡因、普萘洛尔和辛伐他汀）。进行批次测定（50 mL，90 rpm，43 μmol 光子 m-2 s-1，22 °C），包括废水和三种浓度的药物混合物：CHigh、CModerate 和 CEnv。结果表明，这种微藻似乎不受废水中药物的影响，其浓度远高于城市污水中检测到的浓度；此外，它能够比其他微藻物种更好地降解抗生素红霉素和克拉霉素，并将它们从废水中的去除率分别提高 93-65% 和 64-50%。此外，与其他物种相比，它表现出对铵和磷酸盐的高度同化，达到约 9 mgNH4 L-1d-1 和 3 mgPO4 L-1d-1 的值。因此，嗜酸衣藻似乎是一种很有前途的城市污水处理剂。此外，与其他物种相比，它表现出对铵和磷酸盐的高度同化，达到约 9 mgNH4 L-1d-1 和 3 mgPO4 L-1d-1 的值。因此，嗜酸衣藻似乎是一种很有前途的城市污水处理剂。此外，与其他物种相比，它表现出对铵和磷酸盐的高度同化，达到约 9 mgNH4 L-1d-1 和 3 mgPO4 L-1d-1 的值。因此，嗜酸衣藻似乎是一种很有前途的城市污水处理剂。