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Cardiac Glycosides as Senolytic Compounds.
Trends in Molecular Medicine ( IF 12.8 ) Pub Date : 2020-01-23 , DOI: 10.1016/j.molmed.2020.01.001
Nadine Martin 1 , Olivier Soriani 2 , David Bernard 1
Affiliation  

The identification of senolytics, compounds that eliminate senescent cells, is presently a key priority given their therapeutic promise in cancer and aging-associated diseases. Two recent papers by Triana-Martínez et al. and Guerrero et al. report the senolytic activity of cardiac glycosides (CGs) and their efficacy in these pathophysiological contexts.

中文翻译:

心脏糖苷作为缓溶化合物。

考虑到它们在癌症和与衰老相关的疾病中的治疗前景,鉴定senolytics(消除衰老细胞的化合物)目前是关键的优先事项。Triana-Martínez等人最近发表了两篇论文。和Guerrero等。报告了强心苷(CGs)的衰老活性及其在这些病理生理学背景下的功效。
更新日期:2020-01-23
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