Background The inefficiency of recording data repeatedly limits the number of studies conducted. Here we illustrate the wider use of data captured as part of the European eNewborn benchmarking programme. Methods We extracted data on 39,529 live-births from 22 weeks 0 days to 31 weeks 6 days gestational age (GA) or ≤1500 g birth weight. We explored relationships between delivery room care and Apgar scores on mortality and bronchopulmonary dysplasia (BPD) and calculated the time needed for each country to detect a clinically relevant change in these outcomes following a hypothetical intervention. Results Early neonatal, neonatal, and in-hospital mortality were 3.90% (95% CI 3.71, 4.09), 6.00% (5.77, 6.24) and 7.57% (7.31, 7.83), respectively. The odds of death were greater with decreasing GA, lower Apgar scores, growth restriction, male sex, multiple birth and no antenatal steroids. Relationships for BPD were similar. The time required for participating countries to achieve 80% power to detect a relevant change in outcomes following a hypothetical intervention in 23–25 weeks’ GA infants ranged from 12 years for neonatal mortality and 22 years for BPD compared to 1 year for the whole network. Conclusions The eNewborn platform offers opportunity to drive efficiencies in benchmarking, quality control and research.

中文翻译：

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使用 eNewborn European Network 数据库评估整个欧洲的早产护理

背景 重复记录数据的低效率限制了进行的研究数量。在这里，我们说明了作为欧洲 eNewborn 基准计划的一部分捕获的数据的更广泛使用。方法 我们提取了 39,529 例活产儿的数据，范围从 22 周 0 天到 31 周 6 天胎龄 (GA) 或≤1500 g 出生体重。我们探讨了产房护理与死亡率和支气管肺发育不良 (BPD) 的 Apgar 评分之间的关​​系，并计算了每个国家在假设干预后检测这些结果的临床相关变化所需的时间。结果 早期新生儿、新生儿和住院死亡率分别为 3.90% (95% CI 3.71, 4.09)、6.00% (5.77, 6.24) 和 7.57% (7.31, 7.83)。随着 GA 降低、Apgar 评分降低、生长受限、男性、多胞胎，没有产前类固醇。BPD 的关系是相似的。在对 23-25 周 GA 婴儿进行假设干预后，参与国达到 80% 的功效以检测结果的相关变化所需的时间范围从新生儿死亡率的 12 年和 BPD 的 22 年到整个网络的 1 年不等. 结论 eNewborn 平台提供了提高基准、质量控制和研究效率的机会。