Social stimuli such as faces attract and retain attention to a greater extent than other objects. Using fMRI, we investigated how the activity of oculomotor and visual brain regions is modulated when participants look towards or away from visual stimuli belonging to different categories (faces and cars). We identified a region within the superior frontal sulcus showing greater difference between anti- and pro-saccades to faces than to cars, and thereby supporting inhibitory control in a social context. In contrast, ventral occipito-temporal regions and the amygdala, which are associated with face perception, showed higher activity for pro-saccades than anti-saccades for faces, but the reverse for cars, suggesting that contextual, top-down mechanisms modulate the functional specialisation of areas involved in perception. In addition, during saccades in the presence of faces, we found increased functional connectivity between the frontal eye-fields and other cortical and subcortical oculomotor structures, namely the inferior frontal eye field, the posterior parietal cortex and the basal ganglia, possibly reflecting the higher demand put on the oculomotor system to inhibit responses to socially salient stimuli. For the first time, these data highlight neural bases for the different orienting responses towards or away from faces as compared to other objects.

中文翻译：

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社会感知驱动与眼动有关的大脑活动：从前扫视和反扫视到脸部的证据。

诸如面孔之类的社会刺激比其他物体更能吸引和保持注意力。使用功能磁共振成像，我们研究了当参与者朝着或远离属于不同类别（面部和汽车）的视觉刺激时，动眼运动和视觉大脑区域的活动是如何被调节的。我们确定了上额沟内的区域，在面对面部的抗扫视和亲扫视之间的差异比对汽车的反斜视和亲扫视的差异更大，从而在社会背景下支持抑制性控制。相比之下，与面部感知相关的腹枕颞区和杏仁核对前扫视的活动性比对脸扫视的活动性高，但是对汽车而言则相反，这表明背景，自上而下的机制调节了功能。涉及感知领域的专业化。此外，在存在面部的扫视过程中，我们发现额叶视野与其他皮质和皮质下动眼结构（即额下眼视野，顶叶后皮质和基底神经节）之间的功能连接性增加，这可能反映了更高的需求动眼系统以抑制对社会重要刺激的反应。这些数据首次突显了与其他对象相比朝向或远离面部的不同定向响应的神经基础。可能反映了动眼系统对抑制对社会重要刺激的反应的需求增加。这些数据首次突显了与其他对象相比朝向或远离面部的不同定向响应的神经基础。可能反映了动眼系统对抑制对社会重要刺激的反应的需求增加。这些数据首次突显了与其他对象相比朝向或远离面部的不同定向响应的神经基础。