Electrochemical sensing signal is easily interfered by substance with similar redox, which is difficult to be eliminated. The adjusting effect of interfacial barrier on electrochemical response was proposed to suppress this interference. Porous reduced graphene oxide encapsulated ZnO microspheres were prepared and used for detecting dopamine. The response to dopamine is enhanced and the responses to ascorbic acid and uric acid are decreased by changing the barrier height. An ultrahigh sensitivity (1240.74 μA mM^-1 cm^-2) with a wide linear range is 1-600 μM and excellent selectivity to dopamine is achieved. Employing the interfacial barrier to adjust electrochemical response is a promising approach to improve the specificity and sensitivity of electrochemical sensors.

电化学感应信号很容易被具有相似氧化还原的物质干扰，很难消除。为了抑制这种干扰，提出了界面势垒对电化学响应的调节作用。制备了多孔还原氧化石墨烯包裹的ZnO微球，并用于检测多巴胺。通过更改阻挡层高度，可以增强对多巴胺的反应，并降低对抗坏血酸和尿酸的反应。线性范围很宽的超高灵敏度（1240.74μAmM ^-1  cm ^-2）为1-600μM ，可实现对多巴胺的出色选择性。利用界面屏障来调节电化学响应是提高电化学传感器的特异性和灵敏度的一种有前途的方法。