Combining plant resistance against virus and vector presents an attractive approach to reduce virus transmission and virus proliferation in crops. Restricted Tobacco-etch virus Movement (RTM) genes confer resistance to potyviruses by limiting their long-distance transport. Recently, a close homologue of one of the RTM genes, SLI1, has been discovered but this gene instead confers resistance to Myzus persicae aphids, a vector of potyviruses. The functional connection between resistance to potyviruses and aphids, raises the question whether plants have a basic defense system in the phloem against biotic intruders. This paper provides an overview on restricted potyvirus phloem transport and restricted aphid phloem feeding and their possible interplay, followed by a discussion on various ways in which viruses and aphids gain access to the phloem sap. From a phloem-biological perspective, hypotheses are proposed on the underlying mechanisms of RTM- and SLI1-mediated resistance, and their possible efficacy to defend against systemic viruses and phloem-feeding vectors.

中文翻译：

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针对病毒和载体的防御：RTM 和 SLI1 介导的马铃薯病毒和蚜虫抗性的韧皮部生物学视角。

将植物对病毒和载体的抗性结合起来，提供了一种减少作物中病毒传播和病毒增殖的有吸引力的方法。烟草蚀刻病毒运动受限 (RTM) 基因通过限制马铃薯Y病毒的长距离运输来赋予其抗性。最近，发现了 RTM 基因 SLI1 的密切同源物，但该基因反而赋予了对桃蚜（马铃薯Y病毒属载体）的抗性。对马铃薯病毒和蚜虫的抗性之间的功能联系提出了一个问题：植物的韧皮部是否具有针对生物入侵者的基本防御系统。本文概述了限制性马铃薯Y病毒属韧皮部运输和限制性蚜虫韧皮部取食及其可能的相互作用，随后讨论了病毒和蚜虫进入韧皮部汁液的各种方式。从韧皮部生物学的角度来看，对 RTM 和 SLI1 介导的耐药性的潜在机制及其防御系统性病毒和韧皮部喂养载体的可能功效提出了假设。