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A simple synthesis of magnetic nanoparticles-supported 4-aminomethylbenzoic acid as a highly efficient and reusable catalyst for synthesis of 2-amino-4 H -chromene derivatives
Research on Chemical Intermediates ( IF 3.3 ) Pub Date : 2017-06-23 , DOI: 10.1007/s11164-017-3008-2
Mohammad Mehdi Khodaei , Abdolhamid Alizadeh , Maryam Haghipour

A new 4-aminomethylbenzoic acid-functionalized Fe3O4 magnetic nanoparticles as a hybrid heterogeneous catalyst was synthesised and characterized by FT-IR, XRD, TGA, TEM, SEM and VSM techniques. The catalytic activity of this nanocatalyst was probed through one-pot synthesis of 2-amino-4H-chromene derivatives from three component reactions of various aldehydes, malononitrile and dimedone. The chemically and thermally stable catalyst was easily recovered using an external magnet and reused for at least five successive runs without significant loss of its activity. The simplicity of the method, high yields of the products, mild reaction conditions and low reaction times are the other advantages of this procedure.



中文翻译:

磁性纳米粒子负载的4-氨基甲基苯甲酸的简单合成方法,是合成2-氨基-4 H-色烯衍生物的高效且可重复使用的催化剂

合成了一种新型的4-氨基甲基苯甲酸官能化的Fe 3 O 4磁性纳米颗粒作为杂相多相催化剂,并通过FT-IR,XRD,TGA,TEM,SEM和VSM技术对其进行了表征。该纳米催化剂的催化活性是通过一锅合成2-氨基-4 H-色烯衍生物来探测的,该衍生物由各种醛,丙二腈和二甲酮的三个组分反应组成。化学和热稳定的催化剂很容易使用外部磁体进行回收,并至少连续五次重复使用,而活性没有明显损失。该方法的另一优点是方法简单,产物产率高,反应条件温和和反应时间短。

更新日期:2017-06-23
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