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Resveratrol Derivative, Trans-3, 5, 4'-Trimethoxystilbene, Prevents the Developing of Atherosclerotic Lesions and Attenuates Cholesterol Accumulation in Macrophage Foam Cells.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2020-02-09 , DOI: 10.1002/mnfr.201901115
Ming Hong 1, 2 , Jinke Li 3 , Siying Li 3 , Mohammed M Almutairi 3
Affiliation  

Recent studies have demonstrated that trans‐3, 5, 4′‐Trimethoxystilbene (TMS), a novel derivative of resveratrol, may suppress the foam cells formation and restrain atherosclerosis in vitro and in vivo. Herein, the molecular mechanisms underlying the protective effects of TMS against atherosclerosis are further delineated.

中文翻译:

白藜芦醇衍生物 Trans-3,5,4'-三甲氧基二苯乙烯可防止动脉粥样硬化病变的发展并减少巨噬细胞泡沫细胞中的胆固醇积累。

最近的研究表明,反式-3,5,4'-三甲氧基二苯乙烯(TMS)是白藜芦醇的一种新型衍生物,可以在体外和体内抑制泡沫细胞的形成并抑制动脉粥样硬化。在此,进一步阐明了 TMS 对抗动脉粥样硬化保护作用的分子机制。
更新日期:2020-02-09
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