We propose here changes to the U.S. government policy on potential pandemic pathogen (PPP) oversight and implementation, emphasizing transparency of the review process and the content of the review, publication of the review in advance, responsible publication of enhanced PPP research, high-level signoff on approvals of enhanced PPP experiments, and the need for a significant effort to establish a common international approach to enhanced PPP work. We advocate that the U.S. government recommend, and non-U.S. government funders and journals adopt, a set of best practices that would extend important considerations of biosafety and biosecurity to all work on enhanced potential pandemic pathogens regardless of funding source.

中文翻译：

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美国对潜在大流行病原体监督和实施政策的拟议变更。

我们在此提议对美国政府关于潜在大流行病原体（PPP）监督和实施的政策进行更改，强调审查过程和审查内容的透明度，预先发表审查，负责任的加强PPP研究的发布，高级批准增强的PPP实验的批准，以及需要做出重大努力以建立通用的国际方法来增强PPP的工作。我们主张美国政府建议并由非美国政府资助者和期刊采用一套最佳实践，以将对生物安全性和生物安全性的重要考虑扩展到所有研究增强型潜在大流行病原体的工作，而不管资金来源如何。