Metal-organic frameworks (MOFs) are a class of crystalline inorganic-organic hybrid porous materials. Sulfur-functionalized MOFs (S-MOFs) are a subclass of MOFs that show some distinctive advantages and extensively studied in solid-phase extraction. In this review, we present a summary on the synthesis and adsorptive application of S-MOFs, and highlight the benefits of sulfur-functionalization. Three most widely used synthesis strategies, namely direct synthesis, post-synthetic modification and composite materials are developed to prepare S-MOFs. Based on hard-soft-acid-base (HSAB) theory, S-MOFs find practical applications in the adsorption of heavy metal ions, especially for mercury. Besides, efficient adsorption of inorganic non-metallic compounds and organic molecules is also reported. Finally, challenges and further perspectives of S-MOFs are presented and discussed in detail to achieve better advancement.

金属有机骨架（MOF）是一类结晶无机有机杂化多孔材料。硫官能化的MOF（S-MOF）是MOF的子类，它显示出一些独特的优势，并在固相萃取中进行了广泛的研究。在这篇综述中，我们对S-MOFs的合成和吸附应用进行了总结，并重点介绍了硫官能化的好处。开发了三种最广泛使用的合成策略，即直接合成，合成后修饰和复合材料以制备S-MOF。S-MOF基于硬软酸碱（HSAB）理论，在重金属离子（尤其是汞）的吸附中发现了实际应用。此外，还报道了无机非金属化合物和有机分子的有效吸附。最后，