Burn is one of the most frequently occurring cases of skin injury which needs immediate medical intervention. The aim of this study is quick and efficient therapy of second degree burns using H.perforatum oil releasing polymeric membranes. 35 adult Wistar Albino rats were used for in vivo experiments. Second degree burn wounds were created on the dorsal side of the rats using a preheated brass rod. Wound zones were photographed and wound areas was calculated on 1st, 4th, 7th, 11th and 16th days of wound formation. Situation of the wound zones were evaluated macroscopically. No adverse effects were met during treatment. At the end of experiment, skin wound zone was dissected with neighbor healthy tissues. Fixed tissues were blocked in paraffin after routine tissue inspection. Microscopic evaluations of the wound situation were done by histopathological and immunohistochemical analyses of the thin tissue specimens taken from blocked tissues. It was confirmed with macroscopic and microscopic evaluations that a more distinct wound healing and a better ratio of newly formed tissue was evident for the wound zones especially treated with oil releasing membranes.

烧伤是最常见的皮肤损伤病例之一，需要立即进行医疗干预。这项研究的目的是使用贯叶连翘快速有效地治疗二度烧伤释放油的聚合物膜。将35只成年Wistar Albino大鼠用于体内实验。使用预热的黄铜棒在大鼠的背侧产生二级烧伤伤口。在伤口形成的第1、4、7、11和16天拍摄伤口区域并计算伤口面积。宏观评估伤口区域的情况。治疗期间未见不良反应。在实验结束时，用邻近的健康组织切开皮肤伤口区域。常规组织检查后，固定的组织被石蜡阻塞。通过组织病理学和免疫组织化学分析对取自阻塞组织的薄组织标本进行伤口状况的显微镜评估。