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Greasing the Wheels of Regeneration.
Neuron ( IF 14.7 ) Pub Date : 2020-01-22 , DOI: 10.1016/j.neuron.2019.11.032
Rafi Kohen 1 , Roman J Giger 2
Affiliation  

In this issue of Neuron, Yang et al. (2020) identify glycerolipid metabolism as a neuron-intrinsic mechanism that regulates axonal growth and regeneration. Shifting glycerolipid metabolism toward increased triglyceride synthesis blocks PNS neuron regeneration, whereas shifting it toward membrane phospholipid synthesis overcomes regeneration failure in CNS neurons.

中文翻译:

润滑再生轮。

在本期《神经元》中,Yang等人。(2020)确定甘油脂代谢是调节轴突生长和再生的神经元内在机制。将甘油脂代谢转移至甘油三酸酯合成增加可阻止PNS神经元再生,而将其转移至膜磷脂合成可克服CNS神经元的再生失败。
更新日期:2020-01-22
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