Schools are increasingly being used to deliver vaccines. In 2015/16 three school-based vaccination programmes were delivered to adolescents in England: human papillomavirus (HPV), meningococcal groups A, C, W and Y disease (MenACWY) and tetanus, diphtheria and polio (Td/IPV). We assessed how school delivery models impact vaccine coverage and how a delivery model for one programme may impact another. Routinely collected national data were analysed to ascertain the school grade achieving highest coverage within each one-dose programme and to compare two-dose delivery models (within year vs across years) for the HPV vaccine. We also assessed whether the HPV delivery model was associated with coverage in other programmes. MenACWY and Td/IPV coverage was highest in younger school grades. Overall similar HPV coverage was achieved with both models (86.7% two doses within one year, 85.8% two doses across two years, p = 0.20). High two-dose HPV coverage in 2015/16 was reported in areas that achieved high HPV coverage in 2013/14 when three doses were required. Areas with high three-dose coverage in 2013/14 achieved higher coverage with a within-one-year approach (92.0% vs 85.2%, p < 0.001), whilst areas reporting low coverage in 2013/14 achieved lower but similar coverage in 2015/16 with both models (79.2% vs 80.9% p = 0.29). MenACWY and Td/IPV coverage were higher in areas with high HPV coverage in 2013/14. Among high HPV coverage areas, MenACWY coverage was higher when HPV doses were delivered within year. School-based programmes should be offered as early as feasible and acceptable to optimise coverage. The choice of delivery model for HPV should take into account local performance and provider experience. Single providers may delivery multiple vaccines and the delivery for one programme may affect the performance of other programmes. Providers should consider local circumstances including past and current vaccine coverage and factors influencing coverage when deciding what delivery model to adopt.

中文翻译：

---

校本疫苗接种计划：对2015/16年度英国学校疫苗接种模式的评估。

学校越来越多地被用来提供疫苗。在2015/16年度，向英格兰的青少年实施了三个基于学校的疫苗接种计划：人乳头瘤病毒（HPV），脑膜炎球菌A，C，W和Y病群（MenACWY）和破伤风，白喉和脊髓灰质炎（Td / IPV）。我们评估了学校的授课模式如何影响疫苗覆盖率，以及一项计划的授课模式如何影响另一项计划。对常规收集的国家数据进行了分析，以确定在每个一剂方案中达到最高覆盖率的学校成绩，并比较两剂HPV疫苗的给药模型（年内还是跨年）。我们还评估了HPV的提供模式是否与其他计划的覆盖率相关。MenACWY和Td / IPV覆盖率在较年轻的学校年级中最高。两种型号均实现了相似的HPV覆盖率（86。一年内两次服用7％，两年内两次服用85.8％，p = 0.20）。据报道，在需要三剂的情况下，在2013/14年实现高HPV覆盖率的地区，2015/16年的两剂HPV覆盖率很高。在2013/14年度三剂量覆盖率较高的地区，采用一年内的方法实现了较高的覆盖率（92.0％对85.2％，p <0.001），而在2013/14年度报告覆盖率较低的地区在2015年覆盖率较低但相似两种型号均为/ 16（79.2％vs 80.9％p = 0.29）。2013/14年HPV覆盖率较高的地区，MenACWY和Td / IPV覆盖率较高。在HPV高覆盖率地区中，当HPV剂量在一年内交付时，MenACWY覆盖率更高。应尽早提供以学校为基础的课程，并且可以接受以优化覆盖范围。HPV交付模式的选择应考虑当地的绩效和提供商的经验。单个提供者可以提供多种疫苗，而一个程序的交付可能会影响其他程序的执行。提供者在决定采用哪种递送方式时应考虑当地情况，包括过去和当前的疫苗覆盖率以及影响覆盖率的因素。