PURPOSE To identify factors associated with Human Papillomavirus (HPV) vaccine series completion among vaccine initiators in Mississippi Medicaid. METHODS 2013-2018 Mississippi Medicaid administrative claims data were analyzed. Female and male beneficiaries aged 9 to 26 years who initiated HPV vaccination in the identification period were assessed for completion of age-appropriate number of recommended doses within a period of 12 months. Sex-stratified multivariable logistic regression was used to examine factors associated with HPV vaccine series completion in the study sample. RESULTS A total of 18,110 female and 18,186 male beneficiaries initiated HPV vaccine between January 1, 2014 and June 30, 2017. Most of the initiators belonged to ages 11 to 12 years, African American race, managed care plans and Central Mississippi public health region. The vaccine series completion rate was 34% for females and 30% for males. Younger age at initiation was a significant predictor of vaccine series completion in both sexes. Specifically, initiators in age groups 9 to 10 and 11 to 12 years, respectively, had greater odds of completion, while initiators aged 15 to 26 years had lower odds of completion compared to initiators aged 13 to 14 years. Female and male beneficiaries in managed care plans (vs. fee-for-service) and of African American race (vs. Caucasians) had lower odds of completing the vaccine series. Female and male beneficiaries who initiated HPV vaccine series with a pediatrician had the highest completion rates. CONCLUSION HPV vaccination series completion rate in Mississippi Medicaid was suboptimal despite the high HPV-related cancer incidence in the state. HPV vaccine series completion is influenced by various sociodemographic factors. There is a need for robust education and public health programs to encourage completion of recommended doses.

中文翻译：

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密西西比州医疗补助计划中影响人乳头瘤病毒（HPV）疫苗接种系列完成的因素。

目的确定密西西比州医疗补助计划中疫苗接种者中与人乳头瘤病毒（HPV）疫苗系列完成有关的因素。方法分析2013-2018年密西西比州医疗补助行政索赔数据。在鉴定期内开始HPV疫苗接种的9至26岁年龄段的男女受益者，应在12个月内完成适合年龄的建议剂量的评估。按性别分层的多变量logistic回归用于研究样本中与HPV疫苗系列完成相关的因素。结果在2014年1月1日至2017年6月30日之间，共有18,110名女性和18186名男性受益人接种了HPV疫苗。大多数接种者属于11至12岁，非洲裔美国人种族，有管理的护理计划和中密西西比州公共卫生区。女性的疫苗系列完成率为34％，男性为30％。起始年龄较小是男女疫苗系列完成的重要预测指标。具体而言，年龄分别在9至10岁和11至12岁年龄组的发起人比13至14岁年龄组的发起人具有更高的完成几率，而年龄15至26岁的发起人具有较低的完成几率。管理式医疗计划（与按服务收费）和非裔美国人种族（与高加索人）中的男女受益者完成疫苗系列的几率较低。与儿科医生一起启动HPV疫苗系列的男女受益者完成率最高。结论尽管该州与HPV相关的癌症发生率很高，但在密西西比州医疗补助计划中，HPV疫苗接种系列的完成率并不理想。HPV疫苗系列的完成受各种社会人口统计学因素的影响。需要有力的教育和公共卫生计划来鼓励完成推荐剂量。