Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative Study.,BMC Geriatrics

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Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative Study.
BMC Geriatrics ( IF 3.4 ) Pub Date : 2020-01-21 , DOI: 10.1186/s12877-020-1430-6
Nina Mielke ₁ , Dörte Huscher _{1,

2} , Antonios Douros _{3,

4,

5} , Natalie Ebert ₁ , Jens Gaedeke ₆ , Markus van der Giet ₆ , Martin K Kuhlmann ₇ , Peter Martus ₈ , Elke Schaeffner ₁

Affiliation

BACKGROUND Older adults have the highest drug utilization due to multimorbidity. Although the number of people over age 70 is expected to double within the next decades, population-based data on their medication patterns are scarce especially in combination with polypharmacy and potentially inappropriate medication (PIM). Our objective was to analyse the frequency of polypharmacy, pattern of prescription (PD) and over-the-counter (OTC) drug usage, and PIMs according to age and gender in a population-based cohort of very old adults in Germany. METHODS Cross-sectional baseline data of the Berlin Initiative Study, a prospective cohort study of community-dwelling adults aged ≥70 years with a standardized interview including demographics, lifestyle variables, co-morbidities, and medication assessment were analysed. Medication data were coded using the Anatomical Therapeutic Chemical (ATC) classification. Age- and sex-standardized descriptive analysis of polypharmacy (≥5 drugs, PD and OTC vs. PD only and regular and on demand drugs vs regular only), medication frequency and distribution, including PIMs, was performed by age (

中文翻译：

在德国社区居民中自我报告的药物：柏林倡议研究的结果。

背景技术由于多发病，老年人具有最高的药物利用率。尽管预计70岁以上的人口数量在未来几十年内将翻一番，但基于人群的用药模式数据却很少，尤其是与多药房和潜在不当用药（PIM）结合使用时。我们的目标是根据德国人口老龄化的人群中的年龄和性别，分析综合药房的频率，处方（PD）和非处方药（OTC）的使用情况以及PIM。方法对柏林倡议研究的横断面基线数据进行了分析，该研究是对年龄≥70岁的社区居住成年人进行的前瞻性队列研究，并进行了标准化的访谈，包括人口统计学，生活方式变量，合并症和药物评估。使用解剖治疗化学（ATC）分类对药物数据进行编码。按年龄和性别标准化的多药店描述性分析（≥5种药物，PD和OTC与仅PD以及常规和按需药物与常规与仅常规），药物频率和分布（包括PIM）按年龄进行（

更新日期：2020-01-22

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