A switch from a petroleum-based to a biobased economy requires the capacity to produce both high-value low-volume and low-value high-volume products. Recent evidence supports the development of microalgae-based microbial cell factories with the objective of establishing environmentally sustainable manufacturing solutions. Diatoms display rich diversity and potential in this regard. We focus on Phaeodactylum tricornutum, a pennate diatom that is commonly found in marine ecosystems, and discuss recent trends in developing the diatom chassis for the production of a suite of natural and genetically engineered products. Both upstream and downstream developments are reviewed for the commercial development of P. tricornutum as a cell factory for a spectrum of marketable products.

中文翻译：

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三角骨检疫：硅藻细胞工厂。

从石油经济转变为生物经济需要具备生产高价值小批量和低价值大批量产品的能力。最近的证据支持以微藻为基础的微生物细胞工厂的发展，目的是建立环境可持续的制造解决方案。硅藻在这方面显示出丰富的多样性和潜力。我们将重点放在海洋生态系统中常见的三角藻硅藻（Phaeodactylum tricornutum）上，并讨论开发用于生产一系列天然和基因工程产品的硅藻底盘的最新趋势。上游和下游开发都经过了审查，以将三角锥假单胞菌作为细胞工厂用于商业产品的商业开发。